Here we used our novel robotic platform Human Vaping Mimetic Real-Time Particle Analyzer (HUMITIPAA) as well as retrospective analysis of COPDGene clinical cohort to reveal toxicity of menthol-flavored e-cigarettes!

In this review, we examine key preclinical and clinical therapeutic and prophylactic approaches that have been applied for treatment of SARS-CoV-2 infection.

In this article, we created a biologically inspired robotic system that quantitatively analyzes submicron and microparticles generated from ECs in real-time while mimicking clinically relevant breathing and vaping topography exactly as happens in humans.

In this manuscript, we demonstrated antiviral and antiviral-independent anti-inflammatory efficacy of nafamostat mesylate, a potent broad-spectrum serine protease inhibitor that blocks host protease activation of the viral spike protein, against highly pathogenic SARS-CoV-2 and seasonal coronaviruses.

This paper describes engineering, assembly and operation of a microfluidically coupled, multi-compartment platform that bidirectionally ‘breathes’ whole cigarette smoke through microchannels of a human lung small airway microfluidic culture device, mimicking how lung cells may experience smoke in vivo.

Here we describe the development of a human lung 'small airway-on-a-chip' containing a differentiated, mucociliary bronchiolar epithelium and an underlying microvascular endothelium that experiences fluid flow, which allows for analysis of organ-level lung pathophysiology in vitro.