Select publications
On-Chip Reconstitution of Uniformly Shear-Sensing 3D Matrix-Embedded Multicellular Blood Microvessel
Advanced Functional Materials 2023
Vo Q; Carlson KA; Chiknas PM; Brocker CN; DaSilva L; Clark E; Park SK; Ajiboye AS; Wier EM; Benam KH. doi: 10.1002/adfm.202304630
Electronic Cigarette Menthol Flavoring is Associated with Increased Inhaled Micro and Sub-micron Particles and Worse Lung Function in Combustion Cigarette Smokers
Chandra D; Bogdanoff RF; Bowler RP; Benam KH. doi: 10.1186/s12931-023-02410-9
BPIFA1 is a Secreted Biomarker of Differentiating Human Airway Epithelium
Frontiers in Cellular and Infection Microbiology 2022
Clifton C; Niemeyer BF; Novak R; Can UI; Hainline K; Benam KH. doi: 10.3389/fcimb.2022.1035566
Untapping Host-targeting Cross-protective Efficacy of Anticoagulants Against SARS-CoV-2
Pharmacology & Therapeutics2022
Niemeyer BF; Benam KH. doi: 10.1016/j.pharmthera.2021.108027
Protocol for the Operation of a Breathing and Vaping Biomimetic Robot to Delineate Real-time Inhaled Particle Profile of Electronic Cigarettes
Bogdanoff RF; Kaiser AJ; Benam KH. doi: 10.1016/j.xpro.2022.101885
Broad Antiviral and Anti-inflammatory Efficacy of Nafamostat against SARS-CoV-2 and Seasonal Coronaviruses in Primary Human Bronchiolar Epithelia
Niemeyer BF; Miller CM; Ledesma-Feliciano C; Morrison JH; Jimenez-Valdes RJ; Clifton C; Poeschla EM; Benam KH. doi: 10.1002/nano.202100123
A Robotic System for Real-time Analysis of Inhaled Submicron and Microparticles
Kaiser AJ; Salem C; Alvarenga BJ; Pagliaro A; Smith KP; Valerio LG Jr; Benam KH. doi: 10.1016/j.isci.2021.103091
Where We Stand: Lung Organotypic Living Systems That Emulate Human-Relevant Host-Environment/Pathogen Interactions
Frontiers in Bioengineering and Biotechnology 2020
Jimenez-Valdes RJ; Can UI; Niemeyer BF; Benam KH. doi: 10.3389/fbioe.2020.00989
Biomimetic Smoking Robot for In Vitro Inhalation Exposure Compatible with Microfluidic Organ Chips
Benam KH; Novak R; Ferrante TC; Choe Y; Ingber DE. doi: 10.1038/s41596-019-0230-y
How the Respiratory Epithelium Senses and Reacts to Influenza Virus
American Journal of Respiratory Cell and Molecular Biology 2018
Benam KH; Denney L; Ho LP. doi: 10.1165/rcmb.2018-0247TR
M1-like Monocytes Are a Major Immunological Determinant of Severity in Previously Healthy Adults with Life-threatening Influenza
Cole SL; Kok WL; Dunning J; Benam KH; Benlahrech A; Repappi E; Drumright L; Powell TJ; Bennett M; MOSAIC Investigators; Dong T; McCauley J; Liew EFY; Taylor S; Cerundolo V; Openshaw P; McMichael AJ; Ho LP. doi: 10.1172/jci.insight.91868
Commendation for Exposing Key Advantage of Organ Chip Approach
Benam KH; Ingber DE. doi: 10.1016/j.cels.2016.11.009
Engineered In Vitro Disease Models
Annual Reviews of Pathology: Mechanisms of Disease 2015
Benam KH; Dauth S; Hassell B; Herland A; Jain A; Jang KJ; Karalis K; Kim HJ; MacQuee L; Mahmoodian R; Musah S; Torisawa Y; van der Meer AD; Villenave R; Yadid M; Parker KK; Ingber DE. doi: 10.1146/annurev-pathol-012414-040418
Involvement of the 4-1BB/4-1BBL Pathway in Control of Monocyte Numbers by Invariant NKT Cells
Cole SL; Benam KH; McMichael AJ; Ho LP. doi: 10.4049/jimmunol.1302385
A Human-Airway-on-a-Chip for the Rapid Identification of Candidate Antiviral Therapeutics and Prophylactics
Nature Biomedical Engineering 2021
Si L; Bai H; Rodas M; Cao W; Oh CY; Jiang A; Moller R; Hoagland D; Oishi K; Horiuchi S; Uhl S; Blanco-Melo D; Albrecht RA; Liu WC; Jordan T; Nilsson-Payant BE; Golynker I; Frere J; Logue J; Haupt R; McGrath M; Weston S; Zhang T; Plebani R; Soong M; Nurani A; Kim SM; Zhu DY; Benam KH; Goyal G; Gilpin SE; Prantil-Baun R; Gygi SP; Powers RK; Carlson KE; Frieman M; tenOever BR; Ingber DE. doi: 10.1038/s41551-021-00718-9
Advanced Microengineered Lung Models for Translational Drug Discovery
Niemeyer BF; Zhao P; Tuder RM; Benam KH. doi: 10.1177/2472555218760217
Breaking the In Vitro Barrier in Respiratory Medicine: Engineered Microphysiological Systems for COPD and Beyond
American Journal of Respiratory and Critical Care Medicine 2018
Benam KH; Königshoff M; Eickelberg O. doi: 10.1164/rccm.201709-1795PP
Matched-Comparative Modeling of Normal and Diseased Human Airway Responses Using a Microengineered Breathing Lung Chip
Benam KH; Novak R; Nawroth J; Hirano-Kobayashi M; Ferrante TC; Choe Y; Prantil-Baun R; Weaver JC; Bahinski A; Parker KK; Ingber DE. doi: 10.1016/j.cels.2016.10.003
Small Airway-on-a-Chip Enables Analysis of Human Lung Inflammation and Drug Responses In Vitro
Benam KH; Villenave R; Lucchesi C; Varone A; Hubeau C; Lee HH; Salmon M; Alves S; Ferrante TC; Weaver J; Bahinski A; Hamilton G; Ingber DE. doi: 10.1038/nmeth.3697
Down Syndrome Is Associated with Altered Frequency and Functioning of Tracheal Multiciliated Cells, and Response to Influenza Virus Infection
Thomas SN; Niemeyer BF; Jimenez-Valdes RJ; Kaiser AJ; Espinosa JM; Sullivan KD; Goodspeed A; Costello JC; Alder JK; Cañas-Arranz R; García-Sastre A; Benam KH. doi: 10.1016/j.isci.2023.107361
For full list of our lab’s publications, visit Dr. Benam’s Google Scholar page.